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Symbol
Name
ID
Nr4a2
nuclear receptor subfamily 4, group A, member 2
MGI:1352456
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
increased susceptibility to induced colitis
abnormal T-helper 1 cell differentiation
abnormal T-helper 17 cell differentiation
increased T-helper 1 cell number
increased CD4-positive, alpha-beta T cell number
decreased regulatory T cell number
abnormal regulatory T cell morphology
abnormal regulatory T cell physiology
Availability Mouse Genotype
Foxp3tm4(YFP/icre)Ayr/Foxp3+
Nr4a2tm1.1Pcn/Nr4a2tm1.1Pcn  (conditional)
Nr4a2tm1.1Pcn/Nr4a2tm1.1Pcn
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+  (conditional)
Nr4a2tm1.1Pcn/Nr4a2tm1.1Pcn
Tg(Lck-cre)1Jtak/0  (conditional)
*
Nr4a2tm1.1Pcn/Nr4a2+
Foxp3tm4(YFP/icre)Ayr/Foxp3+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory